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The Last of Us Returns with a Touch of Realism
The popular HBO series The Last of Us is set to return on April 13, and this season promises to incorporate a more scientifically accurate portrayal of fungi.
The latest trailer suggests that the “zombie fungus” known as cordyceps infects humans via airborne spores, moving away from the dramatized tentacle infection seen in previous adaptations. This depiction aligns more closely with scientific understanding.
Dr. Jim Kronstad, a microbiologist at UBC’s Michael Smith Laboratories, explains, “Fungi love to make spores.” In nature, cordyceps are known for their ability to invade the brains of ants, manipulating them to ascend to higher branches. The fungus subsequently punctures the ant’s head, releasing spores onto the forest floor.
Many fungal infections in humans, including Cryptococcus neoformans, which can lead to meningitis, are transmitted through inhalation of spores. This reflects the actual mechanisms by which certain fungi spread.
Additionally, the series aptly illustrates how cordyceps, which is typically harmless and even edible, adapts to become a dangerous pathogen in response to climate change. A recent study published in Nature by Dr. Kronstad and colleagues emphasizes that a warming climate may facilitate the proliferation of harmful fungi, such as Coccidioides, responsible for valley fever, and Candida auris, which poses significant risks to hospitalized patients due to its resistance to antifungal treatments.
The researchers also highlighted the identification of a new fungal species, Rhodosporidiobolus fluvialis, which was discovered in humans after only being recognized in environmental samples previously.
However, not all fungal interactions are detrimental. Fungi play essential roles in recycling organic materials and act as important carbon sinks. They can also be utilized in the development of innovative materials, including those suitable for use in space. Moreover, fungi are integral to numerous food products, including vegan alternatives.
Dr. Kronstad affirms, “Fungi are super important; it’s phenomenal what they’ve contributed to human society.”
More information: Nicola T. Case et al. Fungal impacts on Earth’s ecosystems, Nature (2025). DOI: 10.1038/s41586-024-08419-4
Citation: New season of The Last of Us has a chance at realism—scientists discuss ‘zombie fungus’ (2025, April 7) retrieved 7 April 2025 from Phys.org
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