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Infertility is a pressing global health issue that impacts approximately 186 million individuals around the world. Among the various causes contributing to female infertility, blockages in the fallopian tubes account for 11% to 67% of cases. In a groundbreaking study published in AIP Advances by researchers from the SIAT Magnetic Soft Microrobots Lab, a cutting-edge solution has been introduced: a magnetically driven robotic microscrew designed to address these fallopian tube obstructions.
According to lead researcher Haifeng Xu, “This innovative technology presents a potentially less invasive option compared to traditional surgical techniques, which typically rely on conventional catheters and guidewires to remove tubal blockages.”
The newly developed microrobot consists of a nonmagnetic photosensitive resin framework, which is coated in a thin layer of iron to impart magnetic capabilities. When subjected to an external magnetic field, the robot can rotate and move in a way that allows it to traverse a glass channel that simulates a fallopian tube environment. In laboratory tests, the microrobot effectively removed a simulated cell cluster blockage, demonstrating its ability to mimic real-life conditions encountered in the female reproductive system. This magnetically controlled navigation is particularly advantageous for maneuvering through the delicate and constricted pathways of the fallopian tubes.
A significant aspect of the microrobot’s innovation lies in its design. The robot features a screw-like body with a helical design, a central cylindrical tube, and a disk-shaped tail. The helical structure is essential for creating the necessary propulsion, while the disk tail enhances the stability of its motion. The rotation of the screw produces a vortex that facilitates the movement of debris towards the tail, effectively aiding in the clearing of obstructions.
During trials, the microrobot showcased both high effectiveness and efficiency in addressing the simulated blockages, as the vortex generated by its rotation successfully moved debris away, ensuring a thorough clearance.
Looking ahead, the research team intends to miniaturize the microrobot and enhance its capabilities further. Plans are also underway to test the microscrew in isolated organ models and integrate in vivo imaging systems, allowing for real-time tracking of the microrobot’s movements and position. Furthermore, there are aspirations to broaden the scope of the robot’s applications in surgical procedures, potentially leading to automatic control systems that could improve the efficacy of blockage removal as well as other treatments.
“Our ultimate objective is to establish a more efficient and minimally invasive option for those dealing with infertility challenges,” Xu emphasized.
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